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Takayuki Nakagawa Selected Research

Sensorineural Hearing Loss

10/2020Insulin-like growth factor 1: role in the auditory system and therapeutic potential in otology.
1/2020Initiation of Supporting Cell Activation for Hair Cell Regeneration in the Avian Auditory Epithelium: An Explant Culture Model.
10/2016Prognostic impact of salvage treatment on hearing recovery in patients with sudden sensorineural hearing loss refractory to systemic corticosteroids: A retrospective observational study.
12/2015Insulin-like growth factor 1: A novel treatment for the protection or regeneration of cochlear hair cells.
5/2014Therapeutic potential of a gamma-secretase inhibitor for hearing restoration in a guinea pig model with noise-induced hearing loss.
1/2014Strategies for developing novel therapeutics for sensorineural hearing loss.
9/2013Insulin-like growth factor 1 inhibits hair cell apoptosis and promotes the cell cycle of supporting cells by activating different downstream cascades after pharmacological hair cell injury in neonatal mice.
1/2013Systemic steroid application caused sudden death of a patient with sudden deafness.
8/2012Audiometric outcomes of topical IGF1 treatment for sudden deafness refractory to systemic steroids.
1/2012Identification of tympanic border cells as slow-cycling cells in the cochlea.
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Takayuki Nakagawa Research Topics

Disease

87Neoplasms (Cancer)
12/2022 - 10/2002
20Pain (Aches)
01/2021 - 10/2002
16Lung Neoplasms (Lung Cancer)
06/2020 - 03/2012
15Carcinoma (Carcinomatosis)
03/2021 - 04/2013
15Sensorineural Hearing Loss
10/2020 - 12/2006
13Inflammation (Inflammations)
01/2021 - 05/2005
13Peripheral Nervous System Diseases (PNS Diseases)
01/2021 - 07/2012
12Melanoma (Melanoma, Malignant)
09/2022 - 07/2013
11Hearing Loss (Hearing Impairment)
10/2020 - 01/2004
10Breast Neoplasms (Breast Cancer)
04/2022 - 04/2013
10Neoplasm Metastasis (Metastasis)
01/2021 - 10/2003
10Hypersensitivity (Allergy)
01/2021 - 07/2012
10Wounds and Injuries (Trauma)
01/2019 - 02/2005
10Hyperalgesia
01/2017 - 10/2002
7Infections
01/2022 - 07/2003
7Neuralgia (Stump Neuralgia)
07/2018 - 10/2002
7Noise-Induced Hearing Loss (Acoustic Trauma)
05/2014 - 02/2005
6Ischemia
10/2021 - 10/2008
6Cold Hypersensitivity
12/2019 - 07/2012
5Adenocarcinoma
09/2020 - 02/2012
5Cystitis
01/2020 - 01/2013
5Carcinogenesis
12/2018 - 01/2012
5Labyrinth Diseases
07/2015 - 03/2004
4Drug-Related Side Effects and Adverse Reactions
07/2019 - 01/2019
4Hemorrhage
04/2019 - 02/2007
4Sudden Hearing Loss (Sudden Deafness)
10/2016 - 08/2012
3Squamous Cell Carcinoma of Head and Neck
12/2022 - 10/2006
3Hypoxia (Hypoxemia)
05/2021 - 03/2016
3Respiratory Insufficiency (Respiratory Failure)
01/2021 - 01/2019
3Neuroblastoma
11/2018 - 10/2008

Drug/Important Bio-Agent (IBA)

16Pharmaceutical PreparationsIBA
12/2019 - 01/2009
14Tyrosine Kinase InhibitorsIBA
01/2017 - 01/2010
12Proteins (Proteins, Gene)FDA Link
01/2022 - 10/2006
12ErbB Receptors (EGF Receptor)IBA
01/2017 - 03/2012
9Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2021 - 10/2009
9HydrogelsIBA
11/2014 - 04/2006
9Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
06/2014 - 04/2009
8Biomarkers (Surrogate Marker)IBA
09/2022 - 01/2013
8MicroRNAs (MicroRNA)IBA
09/2022 - 01/2012
8Messenger RNA (mRNA)IBA
04/2022 - 07/2003
8Oxaliplatin (Eloxatin)FDA LinkGeneric
12/2019 - 07/2012
8CrizotinibIBA
01/2019 - 07/2012
8LigandsIBA
01/2017 - 10/2003
8Gefitinib (Iressa)FDA Link
01/2015 - 03/2012
7Analgesics (Analgesic Drugs)IBA
01/2021 - 10/2002
7Phosphotransferases (Kinase)IBA
01/2021 - 10/2009
7Paclitaxel (Taxol)FDA LinkGeneric
01/2021 - 07/2012
7CytokinesIBA
09/2020 - 09/2004
7Morphine (MS Contin)FDA LinkGeneric
01/2019 - 02/2004
7Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2015 - 07/2012
7GelatinIBA
11/2014 - 10/2007
6Opioid Analgesics (Opioids)IBA
01/2021 - 01/2008
6PlatinumIBA
12/2019 - 07/2012
6Cisplatin (Platino)FDA LinkGeneric
10/2019 - 01/2004
6AnkyrinsIBA
01/2018 - 01/2016
5DNA (Deoxyribonucleic Acid)IBA
01/2022 - 10/2017
5Formaldehyde (Formol)FDA Link
03/2021 - 01/2007
5Taxoids (Taxanes)IBA
01/2021 - 01/2017
5Insulin-Like Growth Factor I (IGF-1)IBA
10/2020 - 04/2006
5Insulin-Like PeptidesIBA
01/2019 - 10/2007
5Glutamic Acid (Glutamate)FDA Link
07/2013 - 01/2004
4RNA (Ribonucleic Acid)IBA
09/2022 - 12/2018
4EnzymesIBA
04/2022 - 02/2005
4AntigensIBA
01/2021 - 10/2002
4Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2019 - 04/2008
4Adrenal Cortex Hormones (Corticosteroids)IBA
10/2018 - 01/2013
4Adenosine Triphosphate (ATP)IBA
07/2018 - 10/2002
4Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
02/2017 - 01/2013
4Reactive Oxygen Species (Oxygen Radicals)IBA
09/2014 - 09/2008
4Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2014 - 10/2009
4Adrenergic Receptors (Adrenergic Receptor)IBA
01/2014 - 07/2008
4SteroidsIBA
01/2013 - 11/2010
3LipidsIBA
05/2022 - 05/2017
3Antiviral Agents (Antivirals)IBA
01/2022 - 07/2013
3Anti-Bacterial Agents (Antibiotics)IBA
10/2021 - 01/2020
3tyrosine receptor (receptor, tyrosine)IBA
01/2021 - 10/2009
3taxaneIBA
01/2021 - 01/2018
3NucleotidesIBA
01/2021 - 10/2002
3Therapeutic UsesIBA
01/2021 - 03/2010
3Liposomes (Liposome)IBA
01/2021 - 01/2017
3Neutralizing AntibodiesIBA
01/2021 - 09/2012
3Fentanyl (Sublimaze)FDA LinkGeneric
01/2021 - 01/2019
3Clodronic Acid (Clodronate)IBA
01/2021 - 01/2017
3Dinoprostone (PGE2)FDA Link
01/2021 - 01/2020
3Telomerase (Telomerase Reverse Transcriptase)IBA
01/2021 - 05/2003
3C-Reactive ProteinIBA
11/2020 - 05/2005
3human ERBB2 proteinIBA
06/2020 - 07/2019
3Biological ProductsIBA
01/2020 - 06/2013
3Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
10/2019 - 11/2015
3ChemokinesIBA
01/2018 - 04/2004
3CalciumIBA
05/2017 - 08/2010
3CarrageenanIBA
03/2015 - 12/2008
3Insulin (Novolin)FDA Link
11/2014 - 04/2008

Therapy/Procedure

38Therapeutics
01/2022 - 03/2004
11Drug Therapy (Chemotherapy)
01/2021 - 01/2009
7Ligation
11/2018 - 04/2004
5Immunotherapy
01/2022 - 01/2017
5Transplantation
01/2015 - 03/2004
4Intravesical Administration
02/2017 - 01/2013
3Injections
12/2019 - 01/2007